Tissue factor-dependent coagulation contributes to α-naphthylisothiocyanate-induced cholestatic liver injury in mice

Separation of concentrated bile acids from hepatic parenchymal cells is a key function of the bile duct epithelial cells (BDECs) that form intrahepatic bile ducts. Using coimmunostaining, we found that tissue factor (TF), the principal activator of coagulation, colocalized with cytokeratin 19, a mar...

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Bibliografiske detaljer
Main Authors: Luyendyk, James P., Cantor, Glenn H., Kirchhofer, Daniel, Mackman, Nigel, Copple, Bryan L., Wang, Ruipeng
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2009
Fag:
Liver and Biliary Tract
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670671/
https://ncbi.nlm.nih.gov/pubmed/19179621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90639.2008
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