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Coagulation-driven platelet activation reduces cholestatic liver injury and fibrosis in mice

BACKGROUND: The coagulation cascade has been shown to participate in chronic liver injury and fibrosis, but the contribution of various thrombin targets, such as protease activated receptors (PARs) and fibrin(ogen), has not been fully described. Emerging evidence suggests that in some experimental s...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Thromb Haemost
Prif Awduron: Joshi, N., Kopec, A. K., O’Brien, K. M., Towery, K. L., Cline-Fedewa, H., Williams, K.J., Copple, B. L., Flick, M. J., Luyendyk, J. P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487795/
https://ncbi.nlm.nih.gov/pubmed/25353084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.12770
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