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Coagulation-driven platelet activation reduces cholestatic liver injury and fibrosis in mice

BACKGROUND: The coagulation cascade has been shown to participate in chronic liver injury and fibrosis, but the contribution of various thrombin targets, such as protease activated receptors (PARs) and fibrin(ogen), has not been fully described. Emerging evidence suggests that in some experimental s...

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Bibliografski detalji
Izdano u:J Thromb Haemost
Glavni autori: Joshi, N., Kopec, A. K., O’Brien, K. M., Towery, K. L., Cline-Fedewa, H., Williams, K.J., Copple, B. L., Flick, M. J., Luyendyk, J. P.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487795/
https://ncbi.nlm.nih.gov/pubmed/25353084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.12770
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