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Sirt1 Protects the Heart from Ischemia/Reperfusion
BACKGROUND: Sirt1, a class III histone deacetylase, retards aging and protects the heart from oxidative stress. We here examined whether Sirt1 is protective against myocardial ischemia/reperfusion (I/R). METHODS AND RESULTS: Protein and mRNA expression of Sirt1 is significantly reduced by I/R. Cardi...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3003297/ https://ncbi.nlm.nih.gov/pubmed/21060073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.110.958033 |
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