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PPARα Association With Sirt1 Suppresses Cardiac Fatty Acid Metabolism in the Failing Heart

BACKGROUND: Heart failure (HF) is accompanied by changes in cardiac metabolism characterized by reduced fatty acid (FA) utilization. However, the underlying mechanism and its causative involvement in the progression of HF are poorly understood. The peroxisome proliferator activated receptor-α (PPARα...

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Bibliografische gegevens
Gepubliceerd in:Circ Heart Fail
Hoofdauteurs: Oka, Shin-ichi, Zhai, Peiyong, Yamamoto, Takanobu, Ikeda, Yoshiyuki, Byun, Jaemin, Hsu, Chiao-Po, Sadoshima, Junichi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651813/
https://ncbi.nlm.nih.gov/pubmed/26443578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.115.002216
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