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PPARα Association With Sirt1 Suppresses Cardiac Fatty Acid Metabolism in the Failing Heart
BACKGROUND: Heart failure (HF) is accompanied by changes in cardiac metabolism characterized by reduced fatty acid (FA) utilization. However, the underlying mechanism and its causative involvement in the progression of HF are poorly understood. The peroxisome proliferator activated receptor-α (PPARα...
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| Veröffentlicht in: | Circ Heart Fail |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4651813/ https://ncbi.nlm.nih.gov/pubmed/26443578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.115.002216 |
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