DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion

DNA damage can induce a tumor suppressive response termed cellular senescence. Damaged senescent cells permanently arrest growth, secrete inflammatory cytokines and other proteins and harbor persistent nuclear foci that contain DNA damage response (DDR) proteins. To understand how persistent damage...

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Detalhes bibliográficos
Main Authors: Rodier, Francis, Muñoz, Denise P., Teachenor, Robert, Chu, Victoria, Le, Oanh, Bhaumik, Dipa, Coppé, Jean-Philippe, Campeau, Eric, Beauséjour, Christian M., Kim, Sahn-Ho, Davalos, Albert R., Campisi, Judith
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2011
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001408/
https://ncbi.nlm.nih.gov/pubmed/21118958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.071340
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