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Ionizing radiation-induced long-term expression of senescence markers in mice is independent of p53 and immune status

Exposure to IR has been shown to induce the formation of senescence markers, a phenotype that coincides with life-long delayed repair and regeneration of irradiated tissues. We hypothesised that IR-induced senescence markers could persist long-term in vivo, possibly contributing to the permanent red...

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Detalhes bibliográficos
Main Authors: Le, Oanh, Rodier, Francis, Fontaine, Francois, Coppe, Jean-Philippe, Campisi, Judith, DeGregori, James, Laverdiére, Caroline, Kokta, Victor, Haddad, Elie, Beauséjour, Christian M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894262/
https://ncbi.nlm.nih.gov/pubmed/20331441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2010.00567.x
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