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Two faces of p53: aging and tumor suppression

The p53 tumor suppressor protein, often termed guardian of the genome, integrates diverse physiological signals in mammalian cells. In response to stress signals, perhaps the best studied of which is the response to DNA damage, p53 becomes functionally active and triggers either a transient cell cyc...

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Autors principals: Rodier, Francis, Campisi, Judith, Bhaumik, Dipa
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190721/
https://ncbi.nlm.nih.gov/pubmed/17942417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm744
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