Building promoter aware transcriptional regulatory networks using siRNA perturbation and deepCAGE

Perturbation and time-course data sets, in combination with computational approaches, can be used to infer transcriptional regulatory networks which ultimately govern the developmental pathways and responses of cells. Here, we individually knocked down the four transcription factors PU.1, IRF8, MYB...

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Detalles Bibliográficos
Autores principales: Vitezic, Morana, Lassmann, Timo, Forrest, Alistair R. R., Suzuki, Masanori, Tomaru, Yasuhiro, Kawai, Jun, Carninci, Piero, Suzuki, Harukazu, Hayashizaki, Yoshihide, Daub, Carsten O.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2010
Materias:
Genomics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001087/
https://ncbi.nlm.nih.gov/pubmed/20724440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq729
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