Building promoter aware transcriptional regulatory networks using siRNA perturbation and deepCAGE

Perturbation and time-course data sets, in combination with computational approaches, can be used to infer transcriptional regulatory networks which ultimately govern the developmental pathways and responses of cells. Here, we individually knocked down the four transcription factors PU.1, IRF8, MYB...

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Detalhes bibliográficos
Main Authors: Vitezic, Morana, Lassmann, Timo, Forrest, Alistair R. R., Suzuki, Masanori, Tomaru, Yasuhiro, Kawai, Jun, Carninci, Piero, Suzuki, Harukazu, Hayashizaki, Yoshihide, Daub, Carsten O.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001087/
https://ncbi.nlm.nih.gov/pubmed/20724440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq729
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