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RECQ5 helicase associates with the C-terminal repeat domain of RNA polymerase II during productive elongation phase of transcription

It is known that transcription can induce DNA recombination, thus compromising genomic stability. RECQ5 DNA helicase promotes genomic stability by regulating homologous recombination. Recent studies have shown that RECQ5 forms a stable complex with RNA polymerase II (RNAPII) in human cells, but the...

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主要な著者: Kanagaraj, Radhakrishnan, Huehn, Daniela, MacKellar, April, Menigatti, Mirco, Zheng, Lu, Urban, Vaclav, Shevelev, Igor, Greenleaf, Arno L., Janscak, Pavel
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001069/
https://ncbi.nlm.nih.gov/pubmed/20705653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq697
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