The human RecQ helicases BLM and RECQL4 cooperate to preserve genome stability

Bacteria and yeast possess one RecQ helicase homolog whereas humans contain five RecQ helicases, all of which are important in preserving genome stability. Three of these, BLM, WRN and RECQL4, are mutated in human diseases manifesting in premature aging and cancer. We are interested in determining t...

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Bibliografiska uppgifter
Huvudupphovsmän: Singh, Dharmendra Kumar, Popuri, Venkateswarlu, Kulikowicz, Tomasz, Shevelev, Igor, Ghosh, Avik K., Ramamoorthy, Mahesh, Rossi, Marie L., Janscak, Pavel, Croteau, Deborah L., Bohr, Vilhelm A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2012
Ämnen:
Genome Integrity, Repair and Replication
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413146/
https://ncbi.nlm.nih.gov/pubmed/22544709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks349
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