The human RecQ helicases BLM and RECQL4 cooperate to preserve genome stability

Bacteria and yeast possess one RecQ helicase homolog whereas humans contain five RecQ helicases, all of which are important in preserving genome stability. Three of these, BLM, WRN and RECQL4, are mutated in human diseases manifesting in premature aging and cancer. We are interested in determining t...

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Autori principali: Singh, Dharmendra Kumar, Popuri, Venkateswarlu, Kulikowicz, Tomasz, Shevelev, Igor, Ghosh, Avik K., Ramamoorthy, Mahesh, Rossi, Marie L., Janscak, Pavel, Croteau, Deborah L., Bohr, Vilhelm A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
Soggetti:
Genome Integrity, Repair and Replication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413146/
https://ncbi.nlm.nih.gov/pubmed/22544709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks349
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