Physical Interaction of RECQ5 Helicase with RAD51 Facilitates Its Anti-recombinase Activity

Homologous recombination (HR) provides an efficient mechanism for error-free repair of DNA double-strand breaks (DSBs). However, HR can be also harmful as inappropriate or untimely HR events can give rise to lethal recombination intermediates and chromosome rearrangements. A critical step of HR is t...

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Bibliografiske detaljer
Main Authors: Schwendener, Sybille, Raynard, Steven, Paliwal, Shreya, Cheng, Anita, Kanagaraj, Radhakrishnan, Shevelev, Igor, Stark, Jeremy M., Sung, Patrick, Janscak, Pavel
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Enzymology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871440/
https://ncbi.nlm.nih.gov/pubmed/20348101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.110478
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