RECQ5 helicase associates with the C-terminal repeat domain of RNA polymerase II during productive elongation phase of transcription

It is known that transcription can induce DNA recombination, thus compromising genomic stability. RECQ5 DNA helicase promotes genomic stability by regulating homologous recombination. Recent studies have shown that RECQ5 forms a stable complex with RNA polymerase II (RNAPII) in human cells, but the...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Kanagaraj, Radhakrishnan, Huehn, Daniela, MacKellar, April, Menigatti, Mirco, Zheng, Lu, Urban, Vaclav, Shevelev, Igor, Greenleaf, Arno L., Janscak, Pavel
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2010
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001069/
https://ncbi.nlm.nih.gov/pubmed/20705653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq697
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares