RECQ5 helicase associates with the C-terminal repeat domain of RNA polymerase II during productive elongation phase of transcription

It is known that transcription can induce DNA recombination, thus compromising genomic stability. RECQ5 DNA helicase promotes genomic stability by regulating homologous recombination. Recent studies have shown that RECQ5 forms a stable complex with RNA polymerase II (RNAPII) in human cells, but the...

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Dettagli Bibliografici
Autori principali: Kanagaraj, Radhakrishnan, Huehn, Daniela, MacKellar, April, Menigatti, Mirco, Zheng, Lu, Urban, Vaclav, Shevelev, Igor, Greenleaf, Arno L., Janscak, Pavel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2010
Soggetti:
Genome Integrity, Repair and Replication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001069/
https://ncbi.nlm.nih.gov/pubmed/20705653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq697
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