RECQ5 helicase associates with the C-terminal repeat domain of RNA polymerase II during productive elongation phase of transcription

It is known that transcription can induce DNA recombination, thus compromising genomic stability. RECQ5 DNA helicase promotes genomic stability by regulating homologous recombination. Recent studies have shown that RECQ5 forms a stable complex with RNA polymerase II (RNAPII) in human cells, but the...

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Bibliografiska uppgifter
Huvudupphovsmän: Kanagaraj, Radhakrishnan, Huehn, Daniela, MacKellar, April, Menigatti, Mirco, Zheng, Lu, Urban, Vaclav, Shevelev, Igor, Greenleaf, Arno L., Janscak, Pavel
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2010
Ämnen:
Genome Integrity, Repair and Replication
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001069/
https://ncbi.nlm.nih.gov/pubmed/20705653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq697
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