Cell lines from MYCN transgenic murine tumours reflect the molecular and biological characteristics of human neuroblastoma

Overexpression of the human MYCN oncogene driven by a tyrosine hydroxylase promoter causes tumours in transgenic mice that recapitulate the childhood cancer neuroblastoma. To establish an in vitro model to study this process, a series of isogenic cell lines were developed from these MYCN-driven muri...

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Bibliografiske detaljer
Main Authors: Cheng, Andy J., Cheng, Ngan Ching, Ford, Jette, Smith, Janice, Murray, Jayne E., Flemming, Claudia, Lastowska, Maria, Jackson, Michael S., Hackett, Christopher S., Weiss, William A., Marshall, Glenn M., Kees, Ursula R., Norris, Murray D., Haber, Michelle
Format: Artigo
Sprog:Inglês
Udgivet: 2007
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000537/
https://ncbi.nlm.nih.gov/pubmed/17449239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2007.03.008
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