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ODC1 is a critical determinant of MYCN oncogenesis and a therapeutic target in neuroblastoma

Neuroblastoma is a frequently lethal childhood tumor in which MYC gene deregulation, commonly as MYCN amplification, portends poor outcome. Identifying the requisite biopathways downstream of MYC may provide therapeutic opportunities. We used transcriptome analyses to show that MYCN-amplified neurob...

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מידע ביבליוגרפי
Main Authors: Hogarty, Michael D., Norris, Murray D., Davis, Kim, Liu, Xueyuan, Evageliou, Nicholas F., Hayes, Candace S., Pawel, Bruce, Guo, Rong, Zhao, Huaqing, Sekyere, Eric, Keating, Joanna, Thomas, Wayne, Cheng, Ngan Ching, Murray, Jayne, Smith, Janice, Sutton, Rosemary, Venn, Nicola, London, Wendy B., Buxton, Allan, Gilmour, Susan K., Marshall, Glenn M, Haber, Michelle
פורמט: Artigo
שפה:Inglês
יצא לאור: 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596661/
https://ncbi.nlm.nih.gov/pubmed/19047152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6866
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