ODC1 is a critical determinant of MYCN oncogenesis and a therapeutic target in neuroblastoma

Neuroblastoma is a frequently lethal childhood tumor in which MYC gene deregulation, commonly as MYCN amplification, portends poor outcome. Identifying the requisite biopathways downstream of MYC may provide therapeutic opportunities. We used transcriptome analyses to show that MYCN-amplified neurob...

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Hlavní autoři: Hogarty, Michael D., Norris, Murray D., Davis, Kim, Liu, Xueyuan, Evageliou, Nicholas F., Hayes, Candace S., Pawel, Bruce, Guo, Rong, Zhao, Huaqing, Sekyere, Eric, Keating, Joanna, Thomas, Wayne, Cheng, Ngan Ching, Murray, Jayne, Smith, Janice, Sutton, Rosemary, Venn, Nicola, London, Wendy B., Buxton, Allan, Gilmour, Susan K., Marshall, Glenn M, Haber, Michelle
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596661/
https://ncbi.nlm.nih.gov/pubmed/19047152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6866
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