ODC1 is a critical determinant of MYCN oncogenesis and a therapeutic target in neuroblastoma

Neuroblastoma is a frequently lethal childhood tumor in which MYC gene deregulation, commonly as MYCN amplification, portends poor outcome. Identifying the requisite biopathways downstream of MYC may provide therapeutic opportunities. We used transcriptome analyses to show that MYCN-amplified neurob...

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Autores principales: Hogarty, Michael D., Norris, Murray D., Davis, Kim, Liu, Xueyuan, Evageliou, Nicholas F., Hayes, Candace S., Pawel, Bruce, Guo, Rong, Zhao, Huaqing, Sekyere, Eric, Keating, Joanna, Thomas, Wayne, Cheng, Ngan Ching, Murray, Jayne, Smith, Janice, Sutton, Rosemary, Venn, Nicola, London, Wendy B., Buxton, Allan, Gilmour, Susan K., Marshall, Glenn M, Haber, Michelle
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596661/
https://ncbi.nlm.nih.gov/pubmed/19047152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6866
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