Cell lines from MYCN transgenic murine tumours reflect the molecular and biological characteristics of human neuroblastoma

Overexpression of the human MYCN oncogene driven by a tyrosine hydroxylase promoter causes tumours in transgenic mice that recapitulate the childhood cancer neuroblastoma. To establish an in vitro model to study this process, a series of isogenic cell lines were developed from these MYCN-driven muri...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Cheng, Andy J., Cheng, Ngan Ching, Ford, Jette, Smith, Janice, Murray, Jayne E., Flemming, Claudia, Lastowska, Maria, Jackson, Michael S., Hackett, Christopher S., Weiss, William A., Marshall, Glenn M., Kees, Ursula R., Norris, Murray D., Haber, Michelle
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000537/
https://ncbi.nlm.nih.gov/pubmed/17449239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2007.03.008
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados