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Computational redesign of endonuclease DNA binding and cleavage specificity
The reprogramming of DNA-binding specificity is an important challenge for computational protein design that tests current understanding of protein–DNA recognition, and has considerable practical relevance for biotechnology and medicine1–6. Here we describe the computational redesign of the cleavage...
Gorde:
| Egile Nagusiak: | , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2006
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2999987/ https://ncbi.nlm.nih.gov/pubmed/16738662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature04818 |
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