Metabolomics Identifies Novel Hnf1α-Dependent Physiological Pathways in Vivo

Mutations in the HNF1A gene cause maturity-onset diabetes of the young type 3, one of the most common genetic causes of non-insulin-dependent (type 2) diabetes mellitus. Although the whole-body Hnf1a-null mouse recapitulates the low insulin levels and high blood glucose observed in human maturity-on...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Bonzo, Jessica A., Patterson, Andrew D., Krausz, Kristopher W., Gonzalez, Frank J.
Formato: Artigo
Idioma:Inglês
Publicado: The Endocrine Society 2010
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999475/
https://ncbi.nlm.nih.gov/pubmed/20943816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0130
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares