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Metabolomic and Genetic Analysis of Biomarkers for PPARα Expression and Activation

Peroxisome proliferator-activated receptor α (PPARα) is a nuclear receptor with manifold effects on intermediary metabolism. To define a set of urinary biomarkers that could be employed to determine the efficacy of PPARα agonists, a metabolomic investigation was undertaken in wild-type and Pparα-nul...

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Detalhes bibliográficos
Main Authors: Zhen, Yueying, Krausz, Kristopher W., Chen, Chi, Idle, Jeffrey R., Gonzalez, Frank J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2084472/
https://ncbi.nlm.nih.gov/pubmed/17550978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2007-0150
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