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Metabolomics Identifies Novel Hnf1α-Dependent Physiological Pathways in Vivo
Mutations in the HNF1A gene cause maturity-onset diabetes of the young type 3, one of the most common genetic causes of non-insulin-dependent (type 2) diabetes mellitus. Although the whole-body Hnf1a-null mouse recapitulates the low insulin levels and high blood glucose observed in human maturity-on...
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Glavni autori: | , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
The Endocrine Society
2010
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2999475/ https://ncbi.nlm.nih.gov/pubmed/20943816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0130 |
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