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CD4 T cell memory derived from young naive cells functions well into old age, but memory generated from aged naive cells functions poorly

Age-related declines in immune function have an impact on both primary and memory responses. In this study, we have examined the ability of naive CD4 T cells from young and aged T cell receptor transgenic mice to establish functional memory. We found that memory cells generated from young CD4 T cell...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Haynes, Laura, Eaton, Sheri M., Burns, Eve M., Randall, Troy D., Swain, Susan L.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299903/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14657384/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2433717100
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