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CD4 T cell memory derived from young naive cells functions well into old age, but memory generated from aged naive cells functions poorly
Age-related declines in immune function have an impact on both primary and memory responses. In this study, we have examined the ability of naive CD4 T cells from young and aged T cell receptor transgenic mice to establish functional memory. We found that memory cells generated from young CD4 T cell...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC299903/ https://ncbi.nlm.nih.gov/pubmed/14657384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2433717100 |
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