Accumulation of NFAT mediates IL-2 expression in memory, but not naïve, CD4(+) T cells

In contrast to naïve CD4(+) T cells, memory CD4(+) T cells rapidly express high levels of effector cytokines in response to antigen stimulation. The molecular mechanism for this specific behavior is not well understood. The nuclear factor of activated T cells (NFAT) family of transcription factors p...

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Autores principales: Dienz, Oliver, Eaton, Sheri M., Krahl, Troy J., Diehl, Sean, Charland, Colette, Dodge, John, Swain, Susan L., Budd, Ralph C., Haynes, Laura, Rincon, Mercedes
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2007
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855411/
https://ncbi.nlm.nih.gov/pubmed/17438271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610442104
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