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CD4 T cell memory derived from young naive cells functions well into old age, but memory generated from aged naive cells functions poorly

Age-related declines in immune function have an impact on both primary and memory responses. In this study, we have examined the ability of naive CD4 T cells from young and aged T cell receptor transgenic mice to establish functional memory. We found that memory cells generated from young CD4 T cell...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Haynes, Laura, Eaton, Sheri M., Burns, Eve M., Randall, Troy D., Swain, Susan L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC299903/
https://ncbi.nlm.nih.gov/pubmed/14657384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2433717100
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