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Bone Marrow Precursor Cells from Aged Mice Generate CD4 T Cells That Function Well in Primary and Memory Responses

Understanding how aging impacts the function of memory CD4 T cells is critical for designing effective vaccines. Our studies show that immunological memory generated during youth functions well into old age, whereas that generated later in life functions poorly. This is the result of declines in the...

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Detalhes bibliográficos
Main Authors: Eaton, Sheri M., Maue, Alexander C., Swain, Susan L., Haynes, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582190/
https://ncbi.nlm.nih.gov/pubmed/18802086
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