Interleukin 2, but Not Other Common γ Chain–Binding Cytokines, Can Reverse the Defect in Generation of Cd4 Effector T Cells from Naive T Cells of Aged Mice

Development of effectors from naive CD4 cells occurs in two stages. The early stage involves activation and limited proliferation in response to T cell receptor (TCR) stimulation by antigen and costimulatory antigen presenting cells, whereas the later stage involves proliferation and differentiation...

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Hlavní autoři: Haynes, Laura, Linton, Phyllis-Jean, Eaton, Sheri M., Tonkonogy, Susan L., Swain, Susan L.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1999
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195647/
https://ncbi.nlm.nih.gov/pubmed/10510091
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