Učitavanje...
Newly generated CD4 T cells in aged animals do not exhibit age-related defects in response to antigen
Using a T cell receptor transgenic (TCR Tg) mouse model, we have shown that TCR Tg CD4 cells from aged mice retain a naive phenotype, but exhibit reduced proliferation and IL-2 production in response to the antigen compared with cells from young mice. We hypothesize that age-related decreases in T c...
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| Glavni autori: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2005
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2213095/ https://ncbi.nlm.nih.gov/pubmed/15781577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041933 |
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