Impact of Post-Thymic Cellular Longevity on the Development of Age-Associated CD4(+) T Cell Defects

Elderly people are at higher risk for infections due to declining cellular and humoral immune responses. Central to this dysfunction is the reduced responsiveness of the naive CD4(+) T cell compartment. Previous data from our laboratory suggest that although defects in the aged naive CD4(+) T cell r...

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Bibliographic Details
Main Authors: Jones, Stephen C., Clise-Dwyer, Karen, Huston, Gail, Dibble, John, Eaton, Sheri, Haynes, Laura, Swain, Susan L.
Format: Artigo
Language:Inglês
Published: 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366213/
https://ncbi.nlm.nih.gov/pubmed/18354168
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