Dna2 Exhibits a Unique Strand End-dependent Helicase Function

Dna2 endonuclease/helicase participates in eukaryotic DNA transactions including cleavage of long flaps generated during Okazaki fragment processing. Its unusual substrate interaction consists of recognition and binding of the flap base, then threading over the 5′-end of the flap, and cleaving perio...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Balakrishnan, Lata, Polaczek, Piotr, Pokharel, Subhash, Campbell, Judith L., Bambara, Robert A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2010
Aiheet:
DNA and Chromosomes
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998112/
https://ncbi.nlm.nih.gov/pubmed/20929864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.165191
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