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Cross talk between the nuclease and helicase activities of Dna2: role of an essential iron–sulfur cluster domain

Dna2 nuclease/helicase is a multitasking protein involved in DNA replication and recombinational repair, and it is important for preservation of genomic stability. Yeast Dna2 protein contains a conserved putative Fe–S (iron–sulfur) cluster signature motif spanning the nuclease active site. We show t...

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Detalhes bibliográficos
Main Authors: Pokharel, Subhash, Campbell, Judith L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439918/
https://ncbi.nlm.nih.gov/pubmed/22684504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks534
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