Zim17/Tim15 links mitochondrial iron–sulfur cluster biosynthesis to nuclear genome stability

Genomic instability is related to a wide-range of human diseases. Here, we show that mitochondrial iron–sulfur cluster biosynthesis is important for the maintenance of nuclear genome stability in Saccharomyces cerevisiae. Cells lacking the mitochondrial chaperone Zim17 (Tim15/Hep1), a component of t...

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Detalhes bibliográficos
Main Authors: Díaz de la Loza, María del Carmen, Gallardo, Mercedes, García-Rubio, María Luisa, Izquierdo, Alicia, Herrero, Enrique, Aguilera, Andrés, Wellinger, Ralf Erik
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152343/
https://ncbi.nlm.nih.gov/pubmed/21511814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr193
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