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Dna2 Exhibits a Unique Strand End-dependent Helicase Function

Dna2 endonuclease/helicase participates in eukaryotic DNA transactions including cleavage of long flaps generated during Okazaki fragment processing. Its unusual substrate interaction consists of recognition and binding of the flap base, then threading over the 5′-end of the flap, and cleaving perio...

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Detalhes bibliográficos
Main Authors: Balakrishnan, Lata, Polaczek, Piotr, Pokharel, Subhash, Campbell, Judith L., Bambara, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998112/
https://ncbi.nlm.nih.gov/pubmed/20929864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.165191
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