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Dna2 Exhibits a Unique Strand End-dependent Helicase Function
Dna2 endonuclease/helicase participates in eukaryotic DNA transactions including cleavage of long flaps generated during Okazaki fragment processing. Its unusual substrate interaction consists of recognition and binding of the flap base, then threading over the 5′-end of the flap, and cleaving perio...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2998112/ https://ncbi.nlm.nih.gov/pubmed/20929864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.165191 |
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