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Characterization of the Endonuclease and ATP-dependent Flap Endo/Exonuclease of Dna2

Two processes, DNA replication and DNA damage repair, are key to maintaining genomic fidelity. The Dna2 enzyme lies at the heart of both of these processes, acting in conjunction with flap endonuclease 1 and replication protein A in DNA lagging strand replication and with BLM/Sgs1 and MRN/X in doubl...

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Detalhes bibliográficos
Main Authors: Fortini, Barbara K., Pokharel, Subhash, Polaczek, Piotr, Balakrishnan, Lata, Bambara, Robert A., Campbell, Judith L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129157/
https://ncbi.nlm.nih.gov/pubmed/21572043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.243071
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