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Characterization of the Endonuclease and ATP-dependent Flap Endo/Exonuclease of Dna2

Two processes, DNA replication and DNA damage repair, are key to maintaining genomic fidelity. The Dna2 enzyme lies at the heart of both of these processes, acting in conjunction with flap endonuclease 1 and replication protein A in DNA lagging strand replication and with BLM/Sgs1 and MRN/X in doubl...

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Autors principals: Fortini, Barbara K., Pokharel, Subhash, Polaczek, Piotr, Balakrishnan, Lata, Bambara, Robert A., Campbell, Judith L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129157/
https://ncbi.nlm.nih.gov/pubmed/21572043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.243071
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