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Characterization of the Endonuclease and ATP-dependent Flap Endo/Exonuclease of Dna2

Two processes, DNA replication and DNA damage repair, are key to maintaining genomic fidelity. The Dna2 enzyme lies at the heart of both of these processes, acting in conjunction with flap endonuclease 1 and replication protein A in DNA lagging strand replication and with BLM/Sgs1 and MRN/X in doubl...

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Bibliografiske detaljer
Main Authors: Fortini, Barbara K., Pokharel, Subhash, Polaczek, Piotr, Balakrishnan, Lata, Bambara, Robert A., Campbell, Judith L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129157/
https://ncbi.nlm.nih.gov/pubmed/21572043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.243071
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