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Flap Endonuclease 1
First discovered as a structure-specific endonuclease that evolved to cut at the base of single-stranded flaps, flap endonuclease (FEN1) is now recognized as a central component of cellular DNA metabolism. Substrate specificity allows FEN1 to process intermediates of Okazaki fragment maturation, lon...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3679248/ https://ncbi.nlm.nih.gov/pubmed/23451868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-biochem-072511-122603 |
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