Загрузка...
Flap Endonuclease 1 Mechanism Analysis Indicates Flap Base Binding Prior to Threading
FEN1 cleaves 5′ flaps at their base to create a nicked product for ligation. FEN1 has been reported to enter the flap from the 5′-end and track to the base. Current binding analyses support a very different mechanism of interaction with the flap substrate. Measurements of FEN1 binding to a flap subs...
Сохранить в:
| Главные авторы: | , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2010
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2966106/ https://ncbi.nlm.nih.gov/pubmed/20739288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.165902 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|