Saccharomyces cerevisiae Flap Endonuclease 1 Uses Flap Equilibration To Maintain Triplet Repeat Stability

Flap endonuclease 1 (FEN1) is a central component of Okazaki fragment maturation in eukaryotes. Genetic analysis of Saccharomyces cerevisiae FEN1 (RAD27) also reveals its important role in preventing trinucleotide repeat (TNR) expansion. In humans such expansion is associated with neurodegenerative...

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Bibliografiset tiedot
Päätekijät: Liu, Yuan, Zhang, Haihua, Veeraraghavan, Janaki, Bambara, Robert A., Freudenreich, Catherine H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2004
Aiheet:
DNA Dynamics and Chromosome Structure
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC387768/
https://ncbi.nlm.nih.gov/pubmed/15082797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.9.4049-4064.2004
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