Saccharomyces cerevisiae Flap Endonuclease 1 Uses Flap Equilibration To Maintain Triplet Repeat Stability

Flap endonuclease 1 (FEN1) is a central component of Okazaki fragment maturation in eukaryotes. Genetic analysis of Saccharomyces cerevisiae FEN1 (RAD27) also reveals its important role in preventing trinucleotide repeat (TNR) expansion. In humans such expansion is associated with neurodegenerative...

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Dades bibliogràfiques
Publicat a:Mol Cell Biol
Autors principals: Liu, Yuan, Zhang, Haihua, Veeraraghavan, Janaki, Bambara, Robert A., Freudenreich, Catherine H.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2004
Matèries:
DNA Dynamics and Chromosome Structure
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387768/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15082797/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.9.4049-4064.2004
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