Quantitative evaluation of siRNA delivery in vivo

Effective small interfering RNA (siRNA)–mediated therapeutics require the siRNA to be delivered into the cellular RNA-induced silencing complex (RISC). Quantitative information of this essential delivery step is currently inferred from the efficacy of gene silencing and siRNA uptake in the tissue. H...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pei, Yi, Hancock, Paula J., Zhang, Hangchun, Bartz, René, Cherrin, Craig, Innocent, Nathalie, Pomerantz, Colin J., Seitzer, Jessica, Koser, Martin L., Abrams, Marc T., Xu, Yan, Kuklin, Nelly A., Burke, Paul A., Sachs, Alan B., Sepp-Lorenzino, Laura, Barnett, Stanley F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2010
Pynciau:
Method
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995415/
https://ncbi.nlm.nih.gov/pubmed/20940339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2255810
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