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Deciphering the role of glucosamine-6-phosphate in the riboswitch action of glmS ribozyme

The GlmS ribozyme is believed to exploit a general acid-base catalytic mechanism in the presence of glucosamine-6-phosphate (GlcN6P) to accelerate self-cleavage by approximately six orders of magnitude. The general acid and general base are not known, and the role of the GlcN6P cofactor is even less...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Xin, Yao, Hamelberg, Donald
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995406/
https://ncbi.nlm.nih.gov/pubmed/20971809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2334110
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