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Deciphering the role of glucosamine-6-phosphate in the riboswitch action of glmS ribozyme
The GlmS ribozyme is believed to exploit a general acid-base catalytic mechanism in the presence of glucosamine-6-phosphate (GlcN6P) to accelerate self-cleavage by approximately six orders of magnitude. The general acid and general base are not known, and the role of the GlcN6P cofactor is even less...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2995406/ https://ncbi.nlm.nih.gov/pubmed/20971809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2334110 |
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