Phosphatase-Inert Glucosamine 6-Phosphate Mimics Serve as Actuators of the glmS Riboswitch

[Image: see text] The glmS riboswitch is unique among gene-regulating riboswitches and catalytic RNAs. This is because its own metabolite, glucosamine-6-phosphate (GlcN6P), binds to the riboswitch and catalytically participates in the RNA self-cleavage reaction, thereby providing a novel negative fe...

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Veröffentlicht in:ACS Chem Biol
Hauptverfasser: Fei, Xiang, Holmes, Thomas, Diddle, Julianna, Hintz, Lauren, Delaney, Dan, Stock, Alex, Renner, Danielle, McDevitt, Molly, Berkowitz, David B., Soukup, Juliane K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273988/
https://ncbi.nlm.nih.gov/pubmed/25254431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500458f
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