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Serum-stable RNA aptamers to urokinase-type plasminogen activator blocking receptor binding
The serine proteinase urokinase-type plasminogen activator (uPA) is widely recognized as a potential target for anticancer therapy. Its association with cell surfaces through the uPA receptor (uPAR) is central to its function and plays an important role in cancer invasion and metastasis. In the curr...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2995398/ https://ncbi.nlm.nih.gov/pubmed/20962041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2338210 |
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