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Serum-stable RNA aptamers to urokinase-type plasminogen activator blocking receptor binding

The serine proteinase urokinase-type plasminogen activator (uPA) is widely recognized as a potential target for anticancer therapy. Its association with cell surfaces through the uPA receptor (uPAR) is central to its function and plays an important role in cancer invasion and metastasis. In the curr...

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Détails bibliographiques
Auteurs principaux: Dupont, Daniel Miotto, Madsen, Jeppe Buur, Hartmann, Roland Karl, Tavitian, Bertrand, Ducongé, Frédéric, Kjems, Jørgen, Andreasen, Peter André
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995398/
https://ncbi.nlm.nih.gov/pubmed/20962041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2338210
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