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Serum-stable RNA aptamers to urokinase-type plasminogen activator blocking receptor binding

The serine proteinase urokinase-type plasminogen activator (uPA) is widely recognized as a potential target for anticancer therapy. Its association with cell surfaces through the uPA receptor (uPAR) is central to its function and plays an important role in cancer invasion and metastasis. In the curr...

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Autors principals: Dupont, Daniel Miotto, Madsen, Jeppe Buur, Hartmann, Roland Karl, Tavitian, Bertrand, Ducongé, Frédéric, Kjems, Jørgen, Andreasen, Peter André
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995398/
https://ncbi.nlm.nih.gov/pubmed/20962041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2338210
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