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Serum-stable RNA aptamers to urokinase-type plasminogen activator blocking receptor binding

The serine proteinase urokinase-type plasminogen activator (uPA) is widely recognized as a potential target for anticancer therapy. Its association with cell surfaces through the uPA receptor (uPAR) is central to its function and plays an important role in cancer invasion and metastasis. In the curr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dupont, Daniel Miotto, Madsen, Jeppe Buur, Hartmann, Roland Karl, Tavitian, Bertrand, Ducongé, Frédéric, Kjems, Jørgen, Andreasen, Peter André
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995398/
https://ncbi.nlm.nih.gov/pubmed/20962041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2338210
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