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Urokinase links plasminogen activation and cell adhesion by cleavage of the RGD motif in vitronectin

Components of the plasminogen activation system including urokinase (uPA), its inhibitor (PAI‐1) and its cell surface receptor (uPAR) have been implicated in a wide variety of biological processes related to tissue homoeostasis. Firstly, the binding of uPA to uPAR favours extracellular proteolysis b...

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Podrobná bibliografie
Vydáno v:EMBO Rep
Hlavní autoři: De Lorenzi, Valentina, Sarra Ferraris, Gian Maria, Madsen, Jeppe B, Lupia, Michela, Andreasen, Peter A, Sidenius, Nicolai
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931562/
https://ncbi.nlm.nih.gov/pubmed/27189837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201541681
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