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Urokinase links plasminogen activation and cell adhesion by cleavage of the RGD motif in vitronectin

Components of the plasminogen activation system including urokinase (uPA), its inhibitor (PAI‐1) and its cell surface receptor (uPAR) have been implicated in a wide variety of biological processes related to tissue homoeostasis. Firstly, the binding of uPA to uPAR favours extracellular proteolysis b...

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Détails bibliographiques
Publié dans:EMBO Rep
Auteurs principaux: De Lorenzi, Valentina, Sarra Ferraris, Gian Maria, Madsen, Jeppe B, Lupia, Michela, Andreasen, Peter A, Sidenius, Nicolai
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931562/
https://ncbi.nlm.nih.gov/pubmed/27189837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201541681
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