Angiogenin abolishes cell-free protein synthesis by specific ribonucleolytic inactivation of ribosomes.

Angiogenin is a potent inhibitor of cell-free protein synthesis. When incubated with rabbit reticulocyte lysate at a concentration of 40-60 nM, it completely abolishes the capacity of the lysate to support protein synthesis. The inhibition appears to be due to its ribonucleolytic activity since it (...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	St Clair, D K, Rybak, S M, Riordan, J F, Vallee, B L
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1987
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299536/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3479795/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.23.8330
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